In the bone marrow, red blood cells (RBC) are constantly being produced from hematopoietic stem cells (also called progenitor cells), a process called erythropoiesis. The peripheral blood of an individual also contains a host of progenitor cells that can be induced to undergo erythropoiesis. We are developing culture techniques to maximize the production of red blood cells from peripheral blood for the study of erythropoiesis. This involves exploration of the use of synthetic scaffolds environments for blood production and also interactions with stromal cells. The eventual aim being to manufacture enough RBC ...
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