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Professor Christiane Berger-Schaffitzel

Professor Christiane Berger-Schaffitzel

Professor Christiane Berger-Schaffitzel
MSc(Hannover), PhD(Zurich), Habiliation (ETHZurich)

Professor of Biochemistry

Area of research

Ribosomal complexes in protein targeting, translocation and quality control

Office B floor
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

+44 (0) 117 39 41869

Summary

Biography

Christiane Berger-Schaffitzel’s research combines molecular biology, in vitro and in vivo biochemistry, and single-particle cryo-electron microscopy (cryo-EM) to study the structure and function of macromolecular complexes. She obtained her PhD from the University of Zürich (Switzerland) with Andreas Plückthun establishing ribosome display as an in vitro selection and evolution method for high-affinity antibodies against proteins and nucleic acids. At ETH Zürich (with Nenad Ban), she studied ribosomal complexes involved in co-translational targeting and translocation by electron cryo-microscopy. As a team leader at the European Molecular Biology Laboratory (EMBL) in Grenoble (France) she continued to study large macromolecular complexes in gene expression and metabolic regulation.

Research of the Berger-Schaffitzel lab in Bristol (since 2014) focusses on co-translational membrane protein insertion through the bacterial translocation membrane and translational quality control mechanisms. The work has been supported by major grant funding from the European Research Council (ERC Starting Grant),the European Commission (EC FP7), the Swiss National Science Foundation (SNF), the Baden-Württemberg Stiftung and the Agence Nationale de la Recherche (ANR) among others.

Memberships

Organisations

School of Biochemistry

Other sites

School of Biochemistry staff

Recent publications

View complete publications list in the University of Bristol publications system

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