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Publication - Professor Ian Collinson

    Post-Translational Protein Transport by the Sec Complex


    Allen, W, Collinson, I & Römisch, K, 2019, ‘Post-Translational Protein Transport by the Sec Complex’. Trends in Biochemical Sciences, vol 44., pp. 481-483


    Although it has been studied for 30 years, the mechanism by which secretory proteins are transported post-translationally into the endoplasmic reticulum (ER)has not yet been fully resolved. Recently published structures (Itskanov and Park, Science 2019;363:84–87; Wu, X. et al. Nature 2019;566:136–139)of the heptameric secretory (Sec)complex which mediates post-translational import into the yeast ER shed new light on the process.

    Full details in the University publications repository