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Dr Jonathan Hanley

Dr Jonathan Hanley

Dr Jonathan Hanley
B.A.(Cantab.), Ph.D.(U.C.Lond.)

Reader in Molecular Neuroscience

Area of research

The molecular mechanisms of synaptic plasticity

Office Room G.27
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 331 1944

Research summary

Jonathan Hanley, Reader in Molecular Neuroscience

jon.hanley@bristol.ac.uk

 

Learning and the formation of memories involves alterations in neural circuitry, brought about by changes in synaptic strength, which are in turn underpinned by changes in the molecular machinery of synapses. We use a range of biochemical, molecular and imaging techniques, and we collaborate with electrophysiologists for analysing synaptic function. We study three aspects of synaptic plasticity: AMPA receptor trafficking, dendritic spine morphogenesis and the control of protein translation by microRNAs.

AMPA receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in the brain, and plasticity at ...

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Selected publications

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Recent publications

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View complete publications list in the University of Bristol publications system

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