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Dr Kevin Gaston

Dr Kevin Gaston

Dr Kevin Gaston
B.Sc., Ph.D.

Honorary Reader in Biochemistry

Area of research

Gene regulation

Office Room D.47
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 331 2157

Research summary

The focus of my research is on transcription factors and the roles that these proteins play in tumourigenesis. The aim of this work is to understand the mechanisms that these proteins use to control gene expression and the contribution that they make to a variety of pathological conditions including cervical cancer, prostate cancer and breast cancer.

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Biography

I graduated from Leicester University in 1986 with a B.Sc. in Biological Sciences. I then completed a Ph.D. in gene regulation at the University of Birmingham in 1989. After post-doctoral work at the Pasteur Institute in Paris and the CRUK London Institute I was appointed as a lecturer in Bristol in 1994. I am currently a Reader in Biochemistry.

Current Research

PRH/HHEX

The proline-rich homeodomain protein (PRH or HHEX) is an essential regulator of cell differentiation and cell proliferation. Our most recent work has shown that in breast and prostate cells PRH activates transcription of the gene encoding Endoglin ...

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Links

Selected publications

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Recent publications

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View complete publications list in the University of Bristol publications system

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