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Professor Leo Brady

Professor Leo Brady

Professor Leo Brady
BSc(Macq), DPhil(York)

Professor of Biochemistry

Area of research

Structural biology of pathogenesis

Office C.101d
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Alt. +44 (0) 117 903 5516
Tel. +44 (0) 117 33 11828

Research summary

As a structural biologist, I am interested in understanding biological systems at a molecular level. This is achieved by primarily using the technique of protein crystallography. A principal focus of our studies is the study and exploitation of proteins central to human disease. Our work is interdisciplinary, encompasses both basic and applied studies, and we work in close collaboration with a wide range of academic and industrial groups. 

Career research highlights include:

  • The first structure of a lipase [Nature (1989) 343, 767-770], and two fungal amylases [Biochemistry 29, 6244-6249]. These structures have since contributed to protein engineering studies resulting ...

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Biography

  • Professor of Biochemistry, University of Bristol (2001 - present)
  • Head of the School of Biochemistry, University of Bristol (2009-2014)
  • Reader in Biochemistry, University of Bristol (1996-2001)
  • Lecturer in Biochemistry, University of Bristol (1994-1996)
  • MRC AIDS Senior Fellow, University of York/University of Bristol (1990-1995)
  • Postdoctoral Fellow, University of York (1988-1990)
  • Research Assistant, Dept of Chemistry, University of York (1985-1987)
  • Research Assistant, Yale University, CT, USA (1984-1985)
  • Research Assistant, University of Sydney (1983-1984)

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Recent publications

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View complete publications list in the University of Bristol publications system

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