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Professor Paul Martin

Professor Paul Martin

Professor Paul Martin
BSc(Sus), PhD(Lond)

Professor of Cell Biology

Area of research

Inflammation in repair and cancer

Office F32
School of Medical Sciences,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 331 2298

Research summary

Embryos heal wounds very rapidly and efficiently and without leaving a scar. They appear to do this using a very similar portfolio of cellular tools to those used by embyos to undergo the natural morphogenetic movements of development. We hope that studying these parallels will help us better understand embryonic tissue movements and also suggest ways in which we might make adult tissues repair more efficiently. Using live confocal imaging of transgenic Drosophila embryos expressing gfp-actin in epithelial tissues we have compared repair of laser-generated epithelial wounds with the paradigm morphogenetic process of dorsal closure and show that remarkably similar ...

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Biography

Paul Martin did his undergrad degree at Sussex and then a PhD with Julian Lewis at King’s London, before setting up lab in Oxford Anatomy; he moved to UCL Anatomy where he was for 10 years and then in 2003 moved to a joint position in Bristol’s Biochemistry and Physiology Departments.  His lab works on wound healing and has established models to study repair and inflammation in mouse and zebrafish and Drosophila.  The current twin foci of his lab are to investigate  the genetics  and cell biology of wound inflammation, in order to learn how best to modulate ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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