Ultraviolet Absorption Induces Hydrogen-Atom Transfer in G⋅C Watson–Crick DNA Base Pairs in Solution
26 November 2015
Research led by the School of Chemistry published in Angewandte Chemie
A collaboration led by Katharina Roettger, Gareth Roberts and Andrew Orr-Ewing from the Laser Spectroscopy and Dynamics Group, Alex Henderson and Carmen Galan from the Organic and Biological Section, and Friedrich Temps from Kiel University in Germany has resulted in a paper published this week in Angewandte Chemie. The article, which is featured on the inside cover, examines hydrogen-atom transfer across intermolecular hydrogen bonds in guanine-cytosine DNA base pairs on femtosecond to picosecond timescales after absorption of UV light. It has potential impact for our understanding of how DNA resists UV damage to the genetic code.
The article can be found at Angewandte Chemie volume 54, pages 14719 - 14722 (2015).