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Publication - Professor John Bower

    Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy) carbamates

    Citation

    Hazelden, I, Carmona, RC, Langer, T, Pringle, P & Bower, J, 2018, ‘Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy) carbamates’. Angewandte Chemie - International Edition, vol 57., pp. 5124-5128

    Abstract

    Ligand‐enabled aza‐Heck cyclizations and cascades of N‐(pentafluorobenzoyloxy)carbamates are described. These studies encompass the first examples of efficient non‐biased 6‐exo aza‐Heck cyclizations. The methodology provides direct and flexible access to carbamate protected pyrrolidines and piperidines.

    Full details in the University publications repository