Professor Tom Simpson

Research summary

Tom Simpson is the senior member of the Bristol Polyketides Group comprising members of academic staff from the Schools of Chemistry (Profs Russell Cox and Chris Willis, Drs Matt Crump, John Crosby and Chris Arthur) and Biological Science (Drs Colin Lazarus and Andy Bailey). They have developed an international reputation for their work on all aspects of the chemistry and biosynthesis of polyketide metabolites

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Biography

Place and date of Birth: Dollar, Clackmannanshire, Scotland.  23^rd February, 1947.

Degrees:         (1)        B.Sc. (1st Class Honours), Chemistry, Edinburgh 1969.

                        (2)        Ph.D. Bristol, 1973.

                        (3)        D.Sc. Edinburgh, 1986.

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Recent publications

• Yakasai, A, Davison, J, Wasil, Z, Halo, L, Butts, CP, Lazarus, CM, Bailey, AM, Simpson, TJ & Cox, RJ. ‘Non-Genetic Reprogramming of a Fungal Highly Reducing Polyketide Synthase’, Journal of the American Chemical Society, 133, (pp. 10990-10998), 2011
• Murphy, AC, Fukuda, D, Song, Z, Hothersall, J, Cox, RJ, Willis, CL, Thomas, CM & Simpson, TJ. ‘Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390’, Angewandte Chemie International Edition, 50, (pp. 3271-3274), 2011

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