Aggarwal Research Group

Research

• Research Summary
• Primary publications
• Reviews

Group Members

• Varinder K. Aggarwal
• Current group members
• Former group members

Resources and Activities

• Group activities
• Related links
• Bristol Synthesis Meeting
• Newsletters

Aggarwal Group

Professor Varinder Aggarwal carries out research in the development of new methodology and its application in total synthesis, asymmetric synthesis and catalysis, and detailed understanding of chemical processes. Current members of the research group are shown in the photo.

News

• Dec 2011:  Congratulations to Cath Fletcher for securing the best poster prize on her synthesis of giganin at the conference on 'Recent Advances in Synthesis and Chemical Biology' held at University College, Dublin.

• Oct 2011: The group reports a new class of secondary alkyl organometallic-type reagents based on simple boronic esters in JACS. (pdf 1.2mb) They react with a range of electrophiles with inversion. The paper was highlighted in Nature Chemistry. (pdf, 706kb) Well done Robin and Tim!

• Oct 2011: The group reports the total synthesis of (+)-erogorgiaene and each of its diastereoisomers (4 in total) using lithiation–borylation methodology in JACS. (pdf 1.2mb) Congratulations to Tim, Stefan and Ravi!

• Sept 2011: Dr. Ben Partridge joins Prof. John Hartwig in Berkeley for a post doctoral position.

• July 2011: Congratulations to Muhammad Arshad who has been appointed as an Assistant Professor at the University of the Punjab, in Lahore. Muhammad Arshad’s Ph.D. work and poster prize was highlighted in National Newspapers in Pakistan on 31st May 2011, and in HEC's monthly magazine. (jpg).  Well done Muhammad!

• July 2011: Chun Chen receives the 2011 ICIQ summer school award from Institut Català d'Investigació Química, Spain. Well done Chun!

• July 2011:  Gayle Hallett receives the 2011 Bristol ChemLabS Postgraduate Teaching Prize. Many congratulations!

• June 2011: The group welcomes a new Ph.D. student - Maziar Mohiti, and visiting students - Eva Torres, Juan Francesco Moya and Jason Hui.

• May 2011: The group welcomes two new Ph.D. students - Johnathan Matlock and Phillip Unsworth, and a visiting student - Irantzu Couto.

• May 2011: Graeme Coulthard (3rd year Ph.D.) wins first prize for best final year Ph.D. talk in the Organic and Biological section in the department. Well done Graeme!

• Mar 2011: We report the stereospecific construction of quaternary centers from tertiary boronic esters with >99:1 e.r. in Angewandte. (pdf, 317kb) Article selected by the referees as a VIP. Paper also selected for front issue cover! Many congratulations to Ravi, Vishal, Kostas, Robin and Helen for this great team effort!

• Jan 2011: The prepartion of C-tertiary amines with >98% ee is reported in Angewandte Chemie through the sequence involving lithiation-borylation-amination. (pdf, 296kb) Well done Viktor and Tim.

• Dec 2010: Graeme Coulthard (3rd year Ph.D.) wins the "People's Prize" and Helen Scott (2nd year Ph.D.) wins first prize at the Bristol Pfizer Poster Symposium!

• Nov 2010: We reported the stereoselective protodeboronation of tertiary boronic esters to give tertiary arylalkanes in >96% ee in JACS (pdf, 568kb). Good work Stefan, Ravi and Tim!

• Oct 2010: The new Aggarwal Group web site is online!

• Aug 2010: The group reports the total synthesis of solandelactone E via lithiation-borylation-allylation sequence as the key step in Angewandte (pdf, 341kb). Well done Anna! Paper highlighted on Totally Synthetic.

• June 2010: The group reports new reaction conditions allowing for full chirality transfer in conversion of secondary alcohols into tertiary boronic esters and alcohols using lithiation–borylation reactions in Angewandte (pdf, 362kb). Well done Ros and Viktor!

• May 2010: The group reports in JACS subtle issues related to the selectivity in S-ylide cyclopropanation reactions and their implications towards other related cyclopropanations (pdf, 745kb). Congratulations to Samantha, Chandreyee, Noelia, Emma and Eoghan.

• May 2010: Anna Robinson receives the 2nd prize in 3rd year departmental post-graduate research talks. Well done Anna!

• May 2010: A paper on the asymmetric synthesis of allylsilane appears in Angewandte (pdf, 347kb). Good work Michael and Fang! Paper highlighted in Totally Synthetic.

• April 2010: Muhammad Arshad wins the Best Poster Award at the RSC South West Regional Meeting in Bath. Congrats!

• April 2010: Varinder appears on TV! Have a look.

• March 2010: A lithiation-borylation/aldehyde allylboration paper is published in JACS (pdf, 303kb). Congratulations to Martin, Adeem, José and Stephen!

• Jan 2010: A paper describing Sulfur ylide-mediated epoxidation/aziridination including the synthesis of quinine and quinidine was published in JACS (pdf, 332kb). Congrats to Ona, Muhammad, Abel and Eoghan! Paper highlighted in C&E News and Chemistry World.

• Jan 2010: Matt Webster joins Prof. A. Fürstner for a post doctoral position.

• Dec 2009: Mike Shaw joins Prof. K. C. Nicolaou for a post doctoral position.

• Oct 2009: Varinder receives a European Research Council Advanced Grant.

• Sep 2009: Varinder receives the 2009 SCI Process Chemistry Award sponsored by GSK, Pfizer, and AZ.

• Jun 2009: Ros French receives Best Poster Award in departmental Pfizer poster competition. Well done Ros.

• May 2010: Mike Shaw is awarded a Fulbright Distinguished Scholar Fellowship to join Prof. K. C Nicolaou at Scripps. Well done!

• May 2009: Jonathan Killen is awarded best Ph.D. talk in the organic chemistry section. Congratulations.

• May 2009: Varinder receives the RSC Stereochemistry Award 2009.

• May 2009: The group reports the concept of assembly line synthesis (multiple additions of lithiated carabamtes) in Angewandte (pdf, 296kb). Paper selected for inside cover and highlighted in Synfacts. Congrats to Matt and Guillaume!