Negative feedback makes cells 'sensitive'9 January 2014New research has shown that negative feedback loops in cell signalling systems can be essential for a cell’s ability to perceive the strength of a growth stimulus. Cells lacking the feedback loop became insensitive to the level of the stimulus in a manner similar to a cancerous cell displaying unrestrained growth.
Why do some people develop type 1 diabetes rapidly while others at risk do not?9 January 2014The autoimmune process leading to type 1 diabetes can develop quickly in some children and young people but very slowly in others despite the presence of proteins in their blood indicating an on-going autoimmune process in the pancreas. Thanks to combined funding of over $1 million a new study hopes to understand why some people develop type 1 diabetes very early while others who are known to be at risk are protected for decades.
Blood pressure drug as treatment for dementia12 December 2013A 4p per day drug for high blood pressure could become the first ever treatment for one of the most common forms of dementia within a decade, say two leading charities.
Human neural stem cells could meet the clinical problem of critical limb ischemia26 November 2013New research has shown human neural stem cells could improve blood flow in critical limb ischemia through the growth of new vessels. Critical limb ischemia (CLI) is a disease that severely obstructs arteries and reduces the blood flow to legs and feet. CLI remains an unmet clinical problem and with an ageing population and the rise in type II diabetes, the incidence of CLI is expected to increase.
MRC award for regenerative medicine imaging27 October 2013Regenerative medicine could hold the promise of revolutionising patient care in the 21st century. A research team at the University of Bristol have been awarded £2.77 million that could fast-track the progression of new discoveries in stem cell research from the lab to the bedside of the NHS and benefit patients in the future.