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Dr Celia Gregson

Dr Celia Gregson

Dr Celia Gregson
B.Med.Sci., M.B.,B.S.(Nott.), M.R.C.P.(UK), MSc, CCT, PhD

Consultant Senior Lecturer in Musculoskeletal Medicine

Area of research

Epidemiology of musculoskeletal disease

Musculoskeletal Research Unit,
University of Bristol, Level 1 Learning and Research Building BS10 5NB
(See a map)

+44 (0) 117 41 47842


Celia Gregson is a Consultant Senior Lecturer in Musculoskeletal Medicine at the Musculoskeletal Research Unit (MRU), University of Bristol and is an Honorary Consultant Orthogeriatrician at the Royal United Hospital NHS Foundation Trust in Bath. She qualified in Medicine from the University of Nottingham. Following physician training she was awarded a Wellcome Trust Clinical Research Training Fellowship. She completed a one-year MSc in Epidemiology from the London School of Hygiene and Tropical Medicine and then a PhD at the University of Bristol, during which she set up and still runs the UK DINAG consortium (DXA-databases to Identify Novel Anabolic Genes). She then worked as a Senior Scientist at the MRC Lifecourse Epidemiology Unit at the University of Southampton, prior to taking up an Arthritis Research UK Clinician Scientist Fellowship working on the molecular genetics of High Bone Mass at the University of Bristol.


Celia’s research, funded by the National Osteoporosis Society (2015-2018), has identified persistent (and growing) health inequalities in hip fracture incidence and outcomes. She is PI on the Versus Arthritis funded REDUCE Study, which addresses unwarranted variation in the delivery of hip fracture services in England and Wales (2019-2023).


In 2018, Celia founded the ‘Sub-Saharan African MuSculOskeletal Network’ (SAMSON;, which she now co-directs. This network aims to build musculoskeletal research capacity across the region. Research embedded within this network includes: (i) the IMVASK cohort study (The IMpact of Vertical HIV infection on child and Adolescent Skeletal development in Zimbabwe), a Wellcome Funded collaboration with the LSHTM and Biomedical and Research Training Institute (BRTI) in Harare; (ii) ‘VITamin D for AdoLescents with HIV to reduce musculoskeletal morbidity and ImmunopaThologY (VITALITY): an individually randomised, double-blinded placebo-controlled trial’ in Zimbabwe and Zambia which is EDCTP funded; (iii) Celia is PI on a Wellcome Trust Collaborator Award addressing ‘Fractures in sub-Saharan Africa: Epidemiology, Economic impact and Ethnography’.


Celia chairs the Royal College of Physicians Falls and Fragility Fracture Audit Programme Scientific and Publications Committee and is a member of their Fracture Liaison Service Database Advisory Group. She chairs the British Geriatric Society Falls and Bone Health Section and is chair-elect of the UK National Osteoporosis Guideline Group. She is a Fellow of the Royal College of Physicians of London.


  • Musculoskeletal Osteoporosis Fractures High Bone Mass Osteoarthritis Muscle Falls Ageing Epidemiology


  • Osteoporosis High Bone Mass Disorders Falls and Frailty Osteoarthritis HIV Non-Communicable Diseases

Processes and functions

  • Clinical Epidemiology Genetic Epidemiology


I run a UK-wide study intended to characterise patients with very dense bones, and to identify genetic abnormalities which underlie these. Understanding the causes of high bone mass may help us to identify new ways of treating conditions associated with reduced bone mass, like osteoporosis. This study may also help to shed new light on the cause of other conditions where excess bone occurs, such as osteoarthritis, in which new bone is produced in the form of osteophytes at the edges of worn out joints.

  • bones
  • dense bones
  • genetic abnormalities
  • high bone mass
  • reduced bone mass
  • osteoporosis
  • osteoarthritis
  • Recent publications

    View complete publications list in the University of Bristol publications system

    Networks & contacts

    • Prof Matt Brown & Assoc Prof Emma Duncan University of Queensland Brisbane
    • Prof Bill Fraser University of East Anglia
    • Prof Cyrus Cooper MRC Lifecourse Epidemiology Unit University of Southampton
    • Prof Joern Rittweger Manchester Metropolitan University & German Aerospace Center Cologne

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