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Dr Erik Lenguerrand

Dr Erik Lenguerrand

Dr Erik Lenguerrand

Senior Research Fellow

Area of research

Improving PROM, patient safety and clinical outcome in Orthopaedics and Obstetrics using observational studies, RCTs, registry data and medical electronics records

Musculoskeletal Research Unit,
University of Bristol, Level 1 Learning and Research Building BS10 5NB
(See a map)

+44 (0) 117 41 47869

Summary

Biography

Dr Erik Lenguerrand studied datamanagement, quantitative epidemiology and medical statistics in France at the Universities of Lyon (I and II), University of Bordeaux II(ISPED) and University of Paris V. Following several work placements as datamanager, he started his academic career at the Epidemiological Research and Surveillance Unit in Transport, Occupation and Environment (IFSTTAR) working as a Medical Statistician. He secured an IFSTTAR fellowship and completed a PhD in road safety using the National Road Traffic Accident Police Registry data (BAAC) and the French GAZEL cohort study.

He then moved to the MRC/CSO Social and Publich Health Sciences Unit(Prof Dame Sally Macintyre) in Glasgow in 2008 to work as the main statistican for the Ethnicity and Health Research Programme(Prof Seeromanie Harding), using the DASH (Determinants of Adolescent, now young Adults, Social well-being and Health) study.

Erik joined the University of Bristol in 2012 and is conducting research accross two  clinical areas. He is a member of the Orthopaedic Surgery Group, Musculoskeletal Research Unit led by Prof Ashley Blom, Prof Andrew Judge and Mr Michael Whitehouse. He is  a member of the National Joint Registry(NJR) research team .

He is also a methodologist for the Academic Centre for Women's health at the University of Bristol and Southmead Hospital conducting obstretrics research and led by Dr Christy Burden (previously Research into Safety & Quality led by Prof Tim Draycott). He is currently leading the Data Science team for the Tommy’s National Centre for Maternity Improvement. Erik is an honorary member of the Royal College of Obstetricians and Gynaecologists (RCOG).

 

Orthopaedic research

Erik is co-applicant on the NIHR-funded INFORM research programme (Prof Ashley Blom) investigating infection following hip and knee replacements and comparing the outcomes of the different surgical strategies to treat infection. He is leading one of the programme workpackages, using the NJR and HES data to investigate the risk of revision for prosthetic joint infection(PJI). The epidemiological analyses on the risk factors for hip PJI and knee PJI are now published. He is the lead statistician for the INFORM trial nested within this programme. 

Erik was the main statistican for the NIHR-RfPB ARENA RCT (Dr Wylde) investigating the effectiveness of group physio Group‐Based Outpatient Physical Therapy on Function After Total Knee Replacement. Erik was previously the main statistician for the NIHR RESTORE research programme (Prof Ashley Blom and Prof Paul Dieppe) focusing on improving patient experiences of joint replacement surgery. Findings from the APEX trial can be found here.

Erik is now a core member of the university NJR team undertaking statistical analysis of the National Joint Registry (Prof Ashley Blom, Prof Andrew Judge and Mr Michael Whitehouse), the largest arthroplasty register in the world. This work is contracted by HQIP and involves the production of the NJR Annual Report, and adhoc research investigating the safety and performance of orthopaedic implants, units and surgeons. 

Obstetrics research

As the senior methodologist for the new Academic Centre for Women's health at the University of Bristol and Southmead Hospital,  Erik is providing input in the design of the centre grant application (i.e. IMOX study, ASSIST study funded by Bill & Melinda Gates foundation). He is overseing the methodological aspects of the research activities conducted by the Prompt Maternity Foundation(PMF), a key group  of the Academic centre, including Mr Prajapati, the PMF junior statistician. He is also supporting  the work of the centre medical students andjunior colleagues.

Erik has a particular interest in safety in maternity services and the role of training to improve the quality of care using local birth registry or national birth registry: Erik has designed and lead the analysis of the CSO-funded Thistle study, a stepped-wedge RCT investigating the impact of the interprofessional Prompt training accross all large Scottish maternity units using the SMR02 nation birth registry.

He is currently collaborating with researchers from the Karolinska Institutet to develop time-series models to predict future litigation claims from the rates of adverse maternal and perinatal outcomes using the Sweddish birth registry. Similar work has been conducted in Australia using the Victoria state birth registry.

He is currently leading the Data Science team of the Tommy’s National Centre for Maternity Improvement created in 2019 and led by the RCOG in collaboration with the Royal College of Midwives and several other universities. The Data Science team works involves using the National Maternity and Perinatal Audit (NMPA)  to investigate trend and variations in the rates of stillbirth and preterm birthsacross the UK.  

Activities / Findings

Orthopaedic research

  •  The INFORM research programme investigating infection following hip and knee replacements and comparing the outcomes of the different surgical strategies to treat infection. The epidemiological analyses on the risk factors for hip PJI and knee PJI are now published and the analyses of the INFORM trial are ongoing
  • The NIHR-RfPB ARENA RCT led by Dr Wylde investigating the effectiveness of group physio Group‐Based Outpatient Physical Therapy on Function After Total Knee Replacement
  • The NIHR RESTORE research programme focusing on improving patient experiences of joint replacement surgery. Findings from the APEX trial can be found here.
  • Erik is now a core member of the university NJR team undertaking statistical analysis of the National Joint Registry, the largest arthroplasty register in the world.  This work is contracted by HQIP and involves the production of the NJR Annual Report, and adhoc research investigating the safety and performance of orthopaedic implants, units and surgeons. 

Obstetrics research

  • The Tommy’s National Centre for Maternity Improvement  trend and variations in the rates of stillbirths and preterm births across the UK.  
  • The ASSIST study funded by Bill & Melinda Gates foundation  
  • Prompt Maternity Foundation(PMF) research activities
  • Safety in maternity services and the role of training to improve the quality of care using local birth registry or national birth registry: Erik has designed and lead the analysis of the CSO-funded Thistle study, a stepped-wedge RCT investigating the impact of the interprofessional Prompt training accross all large Scottish maternity units using the SMR02 nation birth registry.
  • Predicting future future litigation claims from the past and current rates of adverse maternal and perinatal outcomes using international birth registry.

Teaching

Erik is a fellow of the Higher Education Academy after completing the CREATE programme in 2018.

He is teaching epidemiology, medical statistics and trials methodology across the different programmes of the Bristol Medical School (MSc Orthopaedic Surgery, MSc Public Health/Epidemiology, MSc Reproduction and Development , iBSc in Clinical Sciences, MB ChB/BDS/BVSc Gateway to Medicine, Dentistry, Veterinary Science) and for academic society(E-learning lectures for the European Federation of Orthopaedics and Traumatology-EFORT).

EL supervises several MD (2 current)  and PhD (1 completed, 1 current) students and one MSc student. He was also the statistical supervisor for a clinical lecturer fellowship trainee (NIHR Health Education England, Clinical Academic Training). 

Keywords

  • Orthopaedics
  • Arthroplasty
  • Infection
  • Revision
  • PROMS
  • Obstetrics
  • Maternal and Perinatal Adverse Outcomes
  • Stillbirth
  • Preterm birth
  • Patient Safety
  • Registry

Processes and functions

  • Registry
  • Randomised controlled trials (RCTs)
  • Observational studies

Methodologies

  • Epidemiology
  • Medical Statistics
  • Survival Analysis
  • Longitudinal Analysis
  • Multilevel Model

Selected publications

Read more >

Recent publications

View complete publications list in the University of Bristol publications system

Networks & contacts

  • NJR
  • RCOG
  • RCM

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