Dementia Research Group

The Dementia Research Group conducts preclinical and clinical research in dementia. We use molecular genetic, biochemical, cell culture-based and neuropathological approaches, as well as cognitive and neuroimaging studies in patients. Our aim is to translate our preclinical findings into applications that benefit patients with dementia. At the heart of this is our focus on the molecular epidemiology and pathogenesis of Alzheimer's disease and related dementias.

Our clinical research is based in the BRACE Centre and our preclinical research is based in the John James Laboratories at Frenchay Hospital. The John James Laboratories also house the Human Tissue Authority-licensed South West Dementia Brain Bank.

The Dementia Research Group is part of the University of Bristol's Institute of Clinical Neurosciences and is a member of the Bristol and Bath Alzheimer's Research UK Network Centre.


Extensive deposition of Aβ in small blood vessels in a patient with severe cerebral amyloid angiopathy associated with Alzheimer's disease

Aβ in small blood vessels in Alzheimer's disease


Group heads: Professor Patrick Kehoe and Professor Seth Love

Executive Assistant (Prof Kehoe): Sam Lamprey

Executive Assistant (Prof Love): Joanna McTiernan

John James Laboratories
Frenchay Hospital
Bristol, BS16 1LE
Tel: +44 (0)117 340 3070
Fax: +44 (0)117 340 6665