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Publication - Dr Cian O'Donnell

    Simplicity, Flexibility, and Interpretability in a Model of Dendritic Protein Distributions

    Citation

    O'Donnell, C, 2019, ‘Simplicity, Flexibility, and Interpretability in a Model of Dendritic Protein Distributions’. Neuron, vol 103., pp. 950-952

    Abstract

    In this issue of Neuron, Fonkeu et al. (2019) present a mathematical model of mRNA and protein synthesis, degradation, diffusion, and trafficking in neuronal dendrites. The model can predict the spatial distribution and temporal dynamics of proteins along dendrites. The authors use the model to account for in situ imaging data of CaMKII⍺ mRNA and protein in hippocampal neurons.

    Full details in the University publications repository