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Dr Cian O'Donnell

Computational & Theoretical Neuroscience

I use computational and mathematical modeling to study synapses, neurons, circuits, and how the brain works.

  • Synaptic plasticity and long-term memory
    Spike-timing-dependent plasticity, memory consolidation, biochemical signalling.
    What computational functions do molecular signals perform for memory?
  • Neural data analysis tools
    Developing analysis tools for "big" neural circuit recording data.
    How can we analyse the activity of more than ~10 neurons at a time?
  • Fragile-X Syndrome and Autism
    What is different about neural circuits in the autistic brain? How does this affect neural coding?
  • Neural noise
    Why is the brain so stochastic?
  • Synaptic integration
    How do single neurons transform complex spatiotemporal inputs into a spike output?

Research keywords

  • Neuroscience
  • Computational Biology
  • Machine Learning