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Dr David Morgan

Dr David Morgan

Dr David Morgan
BSc(Bristol), PhD(Warw)

Reader in Immunology

Office E48
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Fax. +44 (0) 117 331 2091
Tel. +44 (0) 117 331 2021

Research summary

Our laboratory is interested in examining the consequences of CD8+ T cell interactions with antigens expressed by normal tissues and cancers.  Earlier studies showed that priming of naive CD8+ T cells to become either effector CTL, or to be rendered tolerant is determined by a combination of signals mediated by professional antigen-presenting cells such as dendritic cells (DC) as well as normal and tumour cells.

We also know that altering any one of these signals dramatically shifts the balance between immune reactivity and tolerance induction.  The following projects aim to develop a deeper understanding of the cellular and molecular mechanisms ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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