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Professor Christoph Wuelfing

Professor Christoph Wuelfing

Professor Christoph Wuelfing
Dip(Munich), PhD(Munich)

Professor of Immunology

Area of research

The spatiotemporal organisation of T cell signalling

Office G51
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 3312364

Research summary

Group: The Wülfing laboratory

The research focus of the Wuelfing laboratory is to understand how T cell signalling is amplified or attenuated in health and disease. To gain unique access to the system-wide, complex processes driving such signal tuning, we directly determine signalling as it occurs in time and space inside primary T cells activated by antigen presenting cells with large-scale live cell imaging approaches.

Image showing

Activating T cells forming deep invaginations with antigen presenting cell (APC) membrane still attached, as visualized by electron microscopy.

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Live cell imaging with the CD48 APC ligand for the CD2 T cell costimulatory receptor ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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