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Dr Lindsay Nicholson

Dr Lindsay Nicholson

Dr Lindsay Nicholson
BSc, BM,BCh(Wales), PhD(Lond), MRCP, FRCP

Reader in Research

Area of research

Autoimmune inflammation reserach

Office F44
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Fax. +44 (0) 117 331 2089
Tel. +44 (0) 117 331 2088

Research summary

Group: Autoimmune Inflammation Research (AIR)

The focus of most of the research in the laboratory is studies of the cells of the immune system. If you don’t know anything about immunology, you may want to check out our questions and answers, where we have tried to explain autoimmunity for people who haven’t studied immunology.

There are very many different cell types involved in an inflammatory reaction, but it takes at least two types of cell to make an adaptive immune response; an antigen presenting cell and an antigen specific responder cell. Our favourite examples of these are the ...

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Biography

I graduated from Cardiff Medical School and after training as a physician went to King’s College London to complete a PhD studying thyroid autoimmunity (or Grave’s disease), with Paul Banga and Alan McGregor. During my time as a PhD student, I developed a longstanding interest in the mechanisms of T cell recognition and activation. For anyone interested in autoimmune disease, this issue of how pathogenic cells get activated is key.

Trying to answer this question took me from London to Boston, to Vijay Kuchroo’s laboratory. Here we focussed on how peptides with single amino acid substitutions (altered peptide ligands) influence ...

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Selected publications

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Recent publications

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View complete publications list in the University of Bristol publications system

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