Researchers at the MRC IEU have created a range of openly available software tools based on research methods developed within the Unit.
MR Base enables online Mendelian randomization analysis using a comprehensive manually curated database of GWAS studies.
LD Hub supports online LD score regression analysis using a comprehensive manually curated database of GWAS studies.
MELODI is a literature mining platform to identify potential mechanistic pathways between exposures and disease outcomes.
FATHMM predicts the functional effects of genetic variants in coding and non-coding parts of the genome.
mQTLdb is a database of methylation QTL (mQTL) from different stages across the lifecourse.
Genome Tolerance Browser (GTB) visually compares functional prediction algorithms across the genome.
TeMMPo is a literature search tool to quantify the literature for specific disease mechanism.
RbG study planner assists in the planning stages and power assessment of recall by genotype studies.
An integrative approach to predicting haploinsufficient genes
Efficient algorithms for analyzing DNA methylation data
Package to run a phenome scan in UK Biobank