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Details for Dr Jim Spencer

Personal details
Name Dr Jim Spencer
Job title Reader in Microbiology
Department School of Cellular and Molecular Medicine University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications BA(Cantab), PhD(Bristol)
Professional details
Keywords microbial pathogenesis
β-lactams
carbapenems
fluoroquinolones
oxazolidinone linezolid
Areas of expertise My current research centres around the application of rapid kinetic and crystallographic methods to study of the structure, mechanism and inhibition of both serine and metallo-beta-lactamases. I am interested in the molecular mechanisms by which resistance arises to a range of important antibiotic classes. I am also investigating the mechanisms by which P. aeruginosa, establishes infection.