The principle focus of our current work is the function of the early secretory pathway in mammalian cells. We are seeking to develop an understanding of the way in which the cell moves vital components that go to build up the extracellular matrix as well as how cells assemble important structures and organize together in 3D to form tissues. In addition, we are continuing our work on the role of microtubule motor proteins in membrane traffic with a particular emphasis on ER-to-Golgi transport. The lab specializes in the analysis of membrane traffic in mammalian cells using advanced light microscopy techniques, in particular, the imaging of living cells. Our work includes developing imaging technologies and integrating model systems including 3D cultures and zebrafish to develop our research.