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Details for Professor Mumtaz Virji

Personal details
Name Professor Mumtaz Virji
Job title Emeritus Professor
Department School of Cellular and Molecular Medicine University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications BSc, PhD(Leeds)
Professional details
Keywords Mechanisms of Neisseria gonorrhoeae pathogenesis
surface components in virulence
mucosal pathogens and colonisers
mucosal colonisation by commensal neisserial species
meningococcal infection
Moraxella catarrhalis adhesin UspA1
Areas of expertise Past Research

Mechanisms of Neisseria gonorrhoeae pathogenesis: studies on the roles of surface components in virulence.

Molecular mechanisms of interactions of Neisseria meningitidis and Haemophilus influenzae with human endothelial, epithelial and phagocytic cells.

Influence of post-translational modifications of meningococcal pili on their functions

Current Research

Molecular basis of common receptor targeting by Neisseria meningitidis and Haemophilus influenzae and other mucosal pathogens and colonisers

Mechanisms of mucosal colonisation by commensal neisserial species.

Development of in vitro models that mimic post inflammatory state of host target cells to examine the influence of cellular receptor profiles on increased susceptibility to meningococcal infection.

Molecular analysis of the interactions of Neisseria meningitidis and Haemophilus influenzae with polarised human epithelial cells

Mechanisms of Neisseria meningitidis targeting of serum factors and intracellular cytoskeletal protein alpha actinin

Studies on Structure, function and mechanics of the Moraxella catarrhalis adhesin UspA1