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Details for Dr Christopher Jackson

Personal details
Name Dr Christopher Jackson
Job title Senior Research Fellow
Department School of Clinical Sciences University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 928 7777
email:
Qualifications BSc, PhD
Professional details
Membership of professional bodies British Society for Cardiovascular Research (Honorary Secretary)

British Atherosclerosis Society (committee member)
Keywords pathophysiology
atherosclerotic plaque rupture
matrix metalloproteinases
proteolytic enzymes
plaque disruption
unstable murine plaques
Areas of expertise Our work focusses on the pathophysiology of atherosclerotic plaque rupture, primarily using a unique mouse model that we have developed. We are currently investigating the involvement of matrix metalloproteinases and other proteolytic enzymes in plaque disruption and healing; the effects of drugs in clinical use on plaque stability; and novel pathways of plaque destabilisation identified as part of a large-scale genomic and proteomic analysis of unstable murine plaques.