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Details for Dr Anja Teschemacher

Personal details
Name Dr Anja Teschemacher
Job title Senior Lecturer
Department School of Physiology, Pharmacology & Neuroscience University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
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Qualifications Diplom, PhD(Munich)
Professional details
Keywords modulation of neurotransmitter release
intracellular signalling mechanisms
release of neurotransmitters
Neurotransmitters
central neurones
neuromodulators
noradrenaline
intracellular second messenger pathways
Areas of expertise Modulation of Neurotransmitter Release

My main interests are the intracellular signalling mechanisms which control release of neurotransmitters from central neurones. More specifically we are focusing on the following questions:

How do neuromodulators such as
angiotensin II affect release of noradrenaline?

Which intracellular second messenger pathways are responsible for changing the release properties?

What are the physiological consequences of these effects for synaptic transmission, i.e. the neuronal output from a particular brain area?
We are addressing these questions by using a combination of electrophysiological (patch clamp and amperometry), optical (confocal imaging of living brain slice cultures), molecular (viral gene transfer) and pharmacological tools.