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Details for Dr Darryl Hill

Personal details
Name Dr Darryl Hill
Job title Senior Lecturer in Microbiology
Department School of Cellular and Molecular Medicine University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications BSc, PhD(Wales)
Professional details
Keywords microbiology
bacterial infections
bacteria and their human host
neisseria meningitidis
moraxella catarrhalis
haemophilus influenzae
Areas of expertise Bacterial infections of the respiratory tract which lead to localised or disseminated disease are a considerable health and financial burden globally. Our research focuses on understanding the interplay between bacteria (mainly colonisers of the respiratory tract) and their human host during colonisation and progression of disease. By understanding key mechanisms used by bacteria to interact with human cells and tissues therapeutic targets can be identified.

-Molecular basis of receptor targeting by mucosal pathogens which colonise the human nasopharynx and oropharynx. Principally studies focus on Neisseria meningitidis, Moraxella catarrhalis and Haemophilus influenzae.
-Interactions of Neisseria meningitidis with serum components.
-Epithelial cell responses to neisserial infection.
-Bacterial interplay during adhesion to human respiratory epithelia.
-Structure and function analyses of Moraxella catarrhalis surface proteins.
-Bacterial-stem cell interactions in osteomyelitis.