Directory of Experts
Details for Professor Alastair Poole
| Personal details | |
| Name | Professor Alastair Poole |
| Job title | Professor of Pharmacology and Cell Biology |
| Department | School of Physiology and Pharmacology University of Bristol |
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 928 7777 email: public-relations@bristol.ac.uk |
| Qualifications | VetMB, MA, PhD(Cantab), MRCVS |
| Professional details | |
| Membership of professional bodies | I am a committee member of the British Society for Haemostasis and Thrombosis, a Principal Editor for Platelets, on the Editorial Advisory Board for the Journal of Thrombosis and Haemostasis and a full Editorial Board member for the Journal of Biological Chemistry. |
| Keywords | Platelets primary haemostatic system pathological development of thrombosis cell biology of platelets protein kinases platelet function thrombus formation |
| Areas of expertise | Platelets are the smallest cellular component of the blood and are an essential element in the primary haemostatic system. They are able to respond to a wide range of agonists and when activated at the site of blood vessel injury they rapidly aggregate to form a platelet haemostatic plug. Platelets are therefore of central importance in maintaining the physiological integrity of the vascular system and play a major role in the pathological development of thrombosis. Our laboratory is interested in the cell biology of platelets, from the molecular through to the systems level. We are particularly interested in understanding how protein kinases may regulate platelet function and thrombus formation, and use a wide variety of techniques to address these questions. |