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default for PI page turquoise Professor Daniel Robert
Mechanisms of audition in microscale systems

Full contact details
d.robert@bristol.ac.uk
School of Biological Sciences

Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

Research

Using insects as model systems, our research contributes to understanding the foundations of the sense of audition. Audition is investigated at multiple levels, from the molecular basis of mechanoreception to the psychophysics of auditory behaviour. The themes thus far have pertained to auditory directional sensitivity, auditory-guided behaviour, nanometre-range sensitivity, frequency selectivity, and the process of active auditory mechanics.

Male mosquitoes use their antennae to detect the minute air-borne vibrations that ensue from the wingbeats of conspecific females. Biomechanical and neurophysiological measurements have shown that the mosquito's auditory system, endowed with a threshold of about 5 nanometres, is one of the most sensitive mechanoreceptor organs thus far described in animals.

Remarkably, such exquisite sensitivity has been shown to be supported by an active physiological process that is in full agreement with the key operational criteria of active sensation uncovered in vertebrates. Active sensation, the process by which sensory organs actively contribute to the mechano-electrical conversion of information, is therefore now studied in insects. Insects constitute precious model systems for such studies due to their biological diversity, small size, surgical accessibility and amenability to genetic dissection.



Current projects include:
  • Acoustic space perception in insects
  • Micro and nanomechanics of microscale auditory systems
  • Nanomechanics of acoustic sensors: from insect ears to silicon cantilevers

Possible future projects and direction of research:
Our research is aimed at understanding fundamental mechanisms of audition. We investigate unconventional, miniature auditory systems -those of insects- with the prospect of uncovering novel mechanisms that can be implemented in technological devices.

Diseases related to this field of research
Deafness, spatial orientation, acoustic perception, cellular mechanisms

Processes and functions relevant to this work
Acoustic space perception, mechanoreception, nanomechanics, cellular motors, hearing


Techniques in routine use
Vibration analysis of small samples, acoustic and mechanical actuation


Equipment in routine use
Three-dimensional video tracking, microscanning laser Doppler vibrometry electrophysiology

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Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

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Grants and funding

  • BBSRC
  • EPSRC
  • Royal Society

Collaborations

Interdisciplinary Research collaboration in Nanotechnology (Cambridge-UCL-Bristol)

Teaching

Sensory Ecology - how organisms acquire information from their environment.

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Publications, recommended reading and further information

Robert, D & Goepfert MC
Novel Schemes for hearing and orientation in insects
Curr Opin Neurobiol, 2002. 12:715-720

Hudspeth, AJ
Mechanical amplification by hair cells
Curr Opin Neurobiol, 1997. 7:480-486

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Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

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