We work closely with Professor Julian Paton to investigate the roles of angiotensin II, nitric oxide and the neurotransmitter GABA, in the central control mechanisms responsible for maintaining blood pressure at normal levels.
It is vital that blood pressure is tightly regulated in order to supply all major organs with blood. `Essential hypertension' describes the condition where blood pressure is higher than normal over a prolonged period of time. This can lead to atherosclerosis, retinopathy, kidney disease, myocardial infarction and stroke.
Angiotensin II is a peptide that acts on blood vessel walls to modify arterial pressure. Blocking its action brings ...
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