Human podocyte cell line

Originally developed by Prof Saleem and colleagues at the University of Bristol, the colloquially named ‘Saleemocyte’ is known and used world-wide. It is a unique and representative tool for the study of human glomerular disease in-vitro.

The conditionally immortalised podocyte cell line allows an in-vitro process of maturation analogous to the development and maturation of podocytes in-vivo. The result is a homogenous, stable cell source that shows expression of key antigenic markers of differentiated in vivo podocytes. These include the novel podocyte proteins nephrin, podocin, CD2AP and synapodin.

Download more information here (PDF, 565kB) or contact: Andrew.Wilson@bris.ac.uk.