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Dr Fergus Caskey

Translational Public Health Research in Kidney Disease

My research concentrates on the epidemiology and treatment of kidney disease – acute kidney injury, chronic kidney disease and end-stage kidney disease.


Much of my research over the years has involved registries, indeed this was why I chose to undertake my renal training in Bristol, home of the UK Renal Registry. I have been very fortunate to be medical director of UKRR from October 2013 - January 2019 and continue to work closely with colleagues there on ongoing projects, most notably:

  • Why do children with severe chronic kidney disease present late to specialist services? A mixed-methods observational study. (A doctoral research fellowship funded by NIHR for Dr Lucy Plumb.)
  • The European Quality Study (EQUAL), an international prospective cohort study looking at the optimal time to start dialysis in people over 65 years of age ( (Funded by the ERA-EDTA.)
  • Erythropoietin therapy for treating anaemia among haemodialysis patients: associations with survival and comparison of treatment strategies. (A post-doctoral fellowship funded by the MRC for Dr Kate Birnie.)
  • The Prepare for Kidney Care Study – a randomised controlled trial comparing preparation for responsive management with preparation for renal dialysis in multi-morbid, frail older people with end-stage kidney disease ( (Funded by the NIHR HTA Programme.)
  • The High-volume Haemodiafiltration vs High-flux Haemodialysis Registry Trial (H4RT) – a randomised controlled trial using the UKRR and linkage to other healthcare databases to provide efficient follow up (see (Funded by the NIHR HTA Programme.)


The UK Renal Registry collects data on all patients in the UK with end-stage kidney disease (on dialysis or with a kidney transplant) and follows them automatically through electronic data capture. In recent years its remit has been broadened to cover:

  • Acute kidney injury occurring in primary or secondary care
  • Pre-dialysis chronic kidney disease managed in secondary care
  • Dialysis for acute kidney injury
  • Patient-reported outcomes.

For more information about the work of the Registry, please visit


Research keywords

  • Translational research
  • Kidney
  • Big Data

Diseases related to this field of research

  • Chronic Kidney Disease
  • Acute kidney injury
  • Renal failure