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Dr Jennifer Palmer

Dr Jennifer Palmer

Dr Jennifer Palmer
B.Sc.(Soton.), PhD

Senior Research Associate

Area of research

ET-1 mediated reduction of cerebral blood flow in Alzheimer's disease: therapeutic potential of Zibotentan

Oakfield House,
Oakfield Grove, Clifton BS8 2BN
(See a map)

Tel. +44 (0) 117 41 47819

Research summary

My research is focused on how the endothelin system is disrupted in the brain in Alzheimer’s disease. There are differences in the levels of ECE-2 and ECE-1, the activity of ECE-1 and the level of ET-1 in the brain in Alzheimer’s disease compared to controls, and I am interested in why this is, and what effect this may have in patients. There appears to be a link between disruption of the endothelin system and the reduction of cerebral blood flow in Alzheimer’s disease, and part of my research is to investigate the mechanism of this. A large part of my ...

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Over the past 6 years at the University of Bristol I have undertaken and passed a PhD and gone on to gain 4 years of post-doctoral experience. I have published 12 peer-reviewed articles (5 as first author) in well-regarded scientific journals, the majority having an impact factor of ~5, and I have presented a total of 23 platform or poster presentations on aspects of this work at both national and international conferences.

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Recent publications

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