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Dr Neil Davies

Dr Neil Davies

Dr Neil Davies
BSc, MSc (Bristol), PhD

Research Fellow

Office BS5
Oakfield House,
Oakfield Grove, Clifton BS8 2BN
(See a map)

+44 (0) 787 201 8338
+44 (0) 117 33 13370

Summary

I am a statistical epidemiologist within the MRC Integrative Epidemiology Unit with expertise in causal inference methods. The two main areas of my research are pharmacoepidemiology and Mendelian randomization.

I have applied and developed methods of using a statistical approach known as instrumental variable analysis to investigate the causal effects of prescription medications. For example, I have investigated the potential beneficial and adverse effects of anti-depressants, smoking cessation medications and anti-inflammatories. I have used data from large databases of electronic medical records such as the Clinical Practice Research Database and Hospital Episodes Statistics database.

A second area of my research involves developing methods for Mendelian randomization studies. Mendelian randomization uses individual genetic variants of known effects to make inferences about the causal effects of modifiable risk factors for disease. This approach can overcome problems which faced by traditional observational studies.

Biography

2013-2015: Research associate on the “Understanding Health Across the Lifecourse: An Integrated Development Approach” DEVHEALTH (269874) European Research Council.

2011-2012: Research assistant, Medicines and Healthcare products Regulatory Agency (MHRA) grant (SDS 33437) on “Medicines that may promote suicide: pharmacoepidemiological analysis of risk and risk assessment”.

2009-2011: Research assistant, “Alzheimer’s disease and anti-hypertensive medications: evidence from the GPRD”, funded by North Bristol NHS Trust.

2008-2012: PhD Student, “Identification of Causal Treatment Effects in Observational Studies”.

2006-2008: Research Assistant, Centre for Market and Public Organisation.

2005-2006: MSc Economics 

Activities / Findings

I am a statistical epidemiologist within the MRC Integrative Epidemiology Unit with expertise in causal inference methods. The two main areas of my research are pharmacoepidemiology and Mendelian randomization.

I have applied and developed methods of using a statistical approach known as instrumental variable analysis to investigate the causal effects of prescription medications. For example, I have investigated the potential beneficial and adverse effects of anti-depressants, smoking cessation medications and anti-inflammatories. I have used data from large databases of electronic medical records such as the Clinical Practice Research Database and Hospital Episodes Statistics database.

A second area of my research involves developing methods for Mendelian randomization studies. Mendelian randomization uses individual genetic variants of known effects to make inferences about the causal effects of modifiable risk factors for disease. This approach can overcome problems which faced by traditional observational studies.

Teaching

I contribute to the Advanced Epidemiology and Advanced Stata short courses within the school.

Keywords

  • Pharmacoepidemiology Mendelian randomisation Electronic medical records Causal inference

Methodologies

  • Instrumental variable analysis

Recent publications

View complete publications list in the University of Bristol publications system

Networks & contacts

  • Prof George Davey Smith and Prof Frank Windmeijer

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