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Dr Oliver Davis
Dr Oliver Davis
BA(Cantab.), MSc(Nott.), MSc(Kings College London), PhD(Kings College London), PGCert(Kings College London)
Reader in Statistical Genetics
Area of research
Mental health data science: digital epidemiology, genomics and visualisation
Research summary
Genetic variation affects all complex human traits and disorders. However, which DNA variants affect us and how they have their effect depends on the environmental and developmental context. For example, some genetic influences may be apparent only in childhood, or only in the centre of large cities. Our lab uses emerging technologies to collect, analyse and visualize data from large population samples around the world, exploring the dynamic relationship between genotype and phenotype in humans.
We use techniques such as twin model-fitting and genome-wide analysis of ‘omics data, as well as developing our own new statistical and visual analysis approaches ...
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Biography
Oliver read Natural Sciences at the University of Cambridge before studying for an MSc and PhD in social, genetic and developmental psychiatry at the MRC SGDP Centre, King’s College London. After his PhD, he was awarded a Sir Henry Wellcome Fellowship by the Wellcome Trust, spending time at the Wellcome Trust Centre for Human Genetics at the University of Oxford and the European Bioinformatics Unit near Cambridge. Towards the end of his fellowship he established a new lab at UCL in London, before moving to Bristol in 2015. In 2018, Oliver became a Fellow of the Alan Turing Institute, the ...
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Selected publications
- Haworth, CMA & Davis, OSP, 2014, ‘From observational to dynamic genetics’. Frontiers in Genetics, vol 5.
- Davis, OSP, Band, G, Pirinen, M, Haworth, CMA, Meaburn, EL, Kovas, Y, Harlaar, N, Docherty, SJ, Hanscombe, KB, Trzaskowski, M, Curtis, CJC, Strange, A, Freeman, C, Bellenguez, C, Su, Z, Pearson, R, Vukcevic, D, Langford, C, Deloukas, P, Hunt, S, Gray, E, Dronov, S, Potter, SC, Tashakkori-Ghanbaria, A, Edkins, S, Bumpstead, SJ, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Duncanson, A, Jankowski, JAZ, Markus, HS, Mathew, CG, Palmer, CNA, Rautanen, A, Sawcer, SJ, Trembath, RC, Viswanathan, AC & others 2014, ‘The correlation between reading and mathematics ability at age twelve has a substantial genetic component’. Nature Communications, vol 5.
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Recent publications
- , Watson, HJ, Yilmaz, Z, Thornton, LM, Hübel, C, Coleman, JRI, Gaspar, HA, Bryois, J, Hinney, A, Leppä, VM, Mattheisen, M, Medland, SE, Ripke, S, Yao, S, Giusti-Rodríguez, P, Hanscombe, KB, Purves, KL, Adan, RAH, Alfredsson, L, Ando, T, Andreassen, OA, Baker, JH, Berrettini, WH, Boehm, I, Boni, C, Perica, VB, Buehren, K, Burghardt, R, Cassina, M, Cichon, S, Clementi, M, Cone, RD, Courtet, P, Crow, S, Crowley, JJ, Danner, UN, Davis, OSP, Zwaan, Md, Dedoussis, G, Degortes, D & others 2019, ‘Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa’. Nature Genetics, vol 51., pp. 1207-1214
- Kwong, A, Manley, D, Timpson, N, Pearson, R, Heron, J, Sallis, H, Stergiakouli, E, Davis, OS & Leckie, G, 2019, ‘Identifying Critical Points of Trajectories of Depressive Symptoms from Childhood to Young Adulthood’. Journal of Youth and Adolescence, vol 48., pp. 815-827
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