Prostate Testing for Cancer and Treatment (ProtecT)

Prostate cancer is a serious health problem. There are 35,000 new cases every year in the UK, and around 10,000 deaths. The ProtecT study is a research project taking place in nine parts of the UK.

ProtecT study findings

The first major results from the ProtecT study were published on September 15th, 2016. All participants were sent a copy of our results newsletter.  The results were widely reported in the newspapers, TV, radio and on-line. These first results present the outcomes of the men who agreed to be randomised to the active monitoring group or surgery group or radiotherapy group. The groups are compared up to the end of 2015 - over an average of 10 years.  

Results published in the New England Journal of Medicine show that all three treatments result in similar, and very low, rates of death from prostate cancer. Surgery and radiotherapy reduce the risk of cancer progression over time compared with active monitoring, but cause more unpleasant side-effects.

More research is needed to identify the cancers that will progress or spread, and those that do not. Longer follow up is needed to find out how survival, progression and spread of cancer, and quality of life will change over the next 5 to 10 years.

Recent newsletter and publications:

ProtecT study centres

  • Bristol Southmead Hospital
    Lead Urologist: Mr Ed Rowe
  • Newcastle Freeman Hospital
    Lead Urologist: Mr Philip Powell
  • Sheffield Royal Hallamshire Hospital
    Lead Urologist: Mr Derek Rosario
  • Birmingham Queen Elizabeth Hospital
    Lead Urologist: Mr Alan Doherty
  • Cardiff University Hospital of Wales
    Lead Urologist: Professor Howard Kynaston
  • Edinburgh Western General Hospital
    Lead Urologist: Mr Prasad Bollina
  • Cambridge Addenbrookes Hospital
    Lead Urologist: Mr Vincent Gnanapragasam
  • Leicester Leicester General Hospital
    Lead Urologist: Mr Roger Kockelbergh
  • Leeds St James Hospital
    Lead Urologist: Mr Alan Paul

About the study

The aim of the ProtecT study is to find out the best ways of treating prostate cancer.

Read more about the study

Potential collaborators

We welcome collaboration from potential investigators carrying out studies in the field of urological research.

Read more about collaborating


The ProtecT Study
School of Social and Community Medicine
University of Bristol
Canynge Hall
39 Whatley Road
Bristol, BS8 2PS
United Kingdom
Tel: Freephone 0800 783 3167


International Standard Randomised Controlled Trial Number: ISRCTN20141297