Dr Andrew Doherty

Research summary

My research work has been in the pharmacology and trafficking of metabotropic glutamate receptors. Working with Profs Graham Collingridge and David Jane, we were testing phenylglycine derivatives for agonist/antagonists that could distinguish between the group I mGlu receptors. We were also looking at the mechanism of internalisation of mGlu1 receptors.

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Biography

I am the Senior Scientific Officer for the MRC Centre for Synaptic Plasticity. This position has multiple roles within it. I am responsible for the management and maintenance of large, multi-user equipment - such as confocal microscopes and multi-photon microscopes, as well as the training on those systems. I am further responsible for the the development and maintenance of the web site for the MRC Centre for Synaptic Plasticity and for the development of the web site for the School of Physiology and Pharmacology.

I am also a teaching Fellow within the School of Physiology and Pharmacology, teaching on level 2 ...

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Selected publications

• Peineau, S, Bradley, C, Taghibiglou, C, Doherty, A, Bortolotto, Z, Wang, Y & Collingridge, G 2008, ‘The role of GSK-3 in synaptic plasticity’. British Journal of Pharmacology, vol 153., pp. S428 - s437
• Doherty, A 1999, ‘MRC Centre for Synaptic Plasticity’.

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Recent publications

• Nicolas, CSC, Amici, M, Bortolotto, ZA, Doherty, AJ, Csaba, Z, Dournaud, P, Gressens, P, Collingridge, GL & Peineau, SAJ 2013, ‘The role of JAK-STAT signalling within the CNS’. JAK/STAT., pp. 1-10
• Amici, M, Doherty, A, Jo, J, Jane, D, Cho, K, Collingridge, G & Dargan, S 2009, ‘Neuronal calcium sensors and synaptic plasticity’. Biochem Soc Trans, vol 37., pp. 1359 - 1363

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View complete publications list in the University of Bristol publications system