Professor Zafar Bashir

Research summary

Neurones of the brain communicate with one another at specialised junctions, called synapses, through the process of synaptic transmission. Having hundreds or thousands of synapses on individual neurones provides for immense complexity in neuronal signalling. However, a further degree of complexity comes about because the communication between neurones is extremely plastic. This means that the strength of synaptic transmission is not fixed but can be increased or decreased (a process called synaptic plasticity) and this property of synaptic plasticity is one of the crucial processes that enables the brain to learn and to retain memories. Therefore, understanding how synaptic transmission ...

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Selected publications

• Piccinin, S, Cinque, C, Calo, L, Molinaro, G, Battaglia, G, Maggi, L, Nicoletti, F, Melchiorri, D, Eusebi, F, Massey, P & Bashir, Z 2010, ‘Interaction between Ephrins and mGlu5 metabotropic glutamate receptors in the induction of long-term synaptic depression in the hippocampus’. J Neuroscience, vol 30., pp. 2835 - 2843
• Gladding, C, Collett, V, Jia, Z, Bashir, Z, Collingridge, G & Molnar, E 2009, ‘Tyrosine dephosphorylation regulates AMPAR internalisation in mGluR-LTD’. Molecular and Cellular Neuroscience, vol 40(2)., pp. 267 - 279

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Recent publications

• Scott, HL, Tamagnini, F, Narduzzo, KE, Howarth, JL, Bok-Lee, Y, Wong, L, Brown, MW, Warburton, EC, Bashir, ZI & Uney, JB 2012, ‘MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex’. The European journal of neuroscience, vol 36., pp. 2941-8
• Banks, PJ, Bashir, ZI & Brown, MW 2012, ‘Recognition memory and synaptic plasticity in the perirhinal and prefrontal cortices’. Hippocampus, vol 22., pp. 2012-31

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View complete publications list in the University of Bristol publications system