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Unit information: Immunopathology and Applied Immunology in 2020/21

Unit name Immunopathology and Applied Immunology
Unit code PANM33002
Credit points 20
Level of study H/6
Teaching block(s) Teaching Block 4 (weeks 1-24)
Unit director Professor. Wuelfing
Open unit status Not open



3 from level 6/H lecture units and Research Skills unit.

School/department School of Cellular and Molecular Medicine
Faculty Faculty of Life Sciences


Immune responses can have harmful direct effects and side effects. Selected examples of such pathological effects are covered including various autoimmune diseases, allergy and the pathogenesis of asthma. Vaccination has been a success story for immunology, but there are many diseases, both microbial and conditions such as cancer and autoimmune diseases, where vaccines remain to be developed. Here the problems of evading the immune response and designing effective vaccines are covered. While the immune system efficiently recognises tumours, it often fails to eliminate them. Tumours of the immune system and tumour immunity are covered. Lectures in weeks 5-8.


This topic has two aims. It provides a comprehensive coverage of diseases, which develop as a consequence of inappropriate immune responses and as a result of deficiencies in the immune system. Secondly, it provides an introduction to disease processes and how this knowledge is used to manipulate the immune system through vaccination and other immunotherapies to fight infection, allergy, autoimmunity and tumour development.

Intended learning outcomes

Knowledge and Understanding of current topics in immunology and how knowledge of immunology can be applied therapeutically. Familiarity with the scientific literature pertaining to the topic and an ability to evaluate this literature critically.

Teaching details

Lectures, Data Handling Session, Journal Review Session.

Independent Study: Students are expected to study the recommended literature.

Assessment Details

Timed assessment to include 2 essays, one essay to be chosen from each section containing three questions.

Reading and References

Janeway's Immunobiology K Murphy and C Weaver, 9th edition (2017) Garland Science ISBN: 9780815345510

Reviews and primary articles from the current scientific literature.