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Unit information: Receptor signalling and non-drug therapies in 2020/21

Unit name Receptor signalling and non-drug therapies
Unit code PHPH30003
Credit points 20
Level of study H/6
Teaching block(s) Teaching Block 4 (weeks 1-24)
Unit director Professor. Kelly
Open unit status Not open
Pre-requisites

PHPH20011 Principles of Pharmacology 2A

Co-requisites

None

School/department School of Physiology, Pharmacology & Neuroscience
Faculty Faculty of Life Sciences

Description

Students study advanced topics covering receptor signalling, so as to learn how different types of metabotropic receptors (including G-protein-coupled receptors and receptor tyrosine kinases) and intracellular receptors generate their effects, by the modification of levels of intracellular messengers and modification of trafficking of receptor proteins into and out of the cell membrane. The Unit also covers the roles of many of these receptors in the function and dysfunction of cardiovascular disease, and the use of drugs acting at these receptors in the treatment of cardiovascular disease. Novel therapies for disease that are not based around small molecules (such as gene manipulation) are also discussed.

Intended learning outcomes

By the end of the unit, students will be able to demonstrate:

  • An in-depth knowledge and understanding of the advanced topics covered in the unit and an ability to keep abreast with recent developments in the relevant field.
  • The ability to gather information from the primary scientific literature and to critically evaluate the material and appraise competing theories.
  • The ability to integrate information from multiple sources and disseminate it in written accounts.
  • An understanding of the importance of specialist metabotropic receptor pharmacology and of the development of novel therapies.

Teaching details

Lectures

Assessment Details

Timed assessment 90%

The unit will be assessed through a timed assessment in May/June, which contributes 90% of the unit mark.

Coursework 10%

Essay or Data Analysis or Figure Interpretation question

Reading and References

Reviews and primary articles from the current scientific literature (updated by individual lecturers on an annual basis).

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