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for a past academic year. Please see the current academic year for up to date information.
| Unit name |
The Dynamic Proteome |
| Unit code |
BIOC30604 |
| Credit points |
20 |
| Level of study |
H/6
|
| Teaching block(s) |
Teaching Block 1 (weeks 1 - 12)
|
| Unit director |
Professor. Mike Jones |
| Open unit status |
Not open |
| Pre-requisites |
BIOC20002 and BIOC20001
|
| Co-requisites |
None
|
| School/department |
School of Biochemistry |
| Faculty |
Faculty of Life Sciences |
Description including Unit Aims
Students study advanced topics in protein biochemistry. These lectures are split into two elements. The first element, Structure and Dynamics of Biomolecules and Systems, covers techniques used to analyse protein structure and dynamics. The second element, Protein Assembly, looks at how proteins are synthesized and how they fold into their unique 3 dimensional shapes.
Aims:
Structure and Dynamics of Biomolecules and Systems
- The techniques used to study protein structure
- The study of kinetics in enzymes and chemiosmotic systems
- The techniques to study protein dynamics on femtosecond to hour scales
- The synthesis of proteins by the ribosomes
Protein Assembly
- Protein structure from bonds to macromolecular complexes
- Sequence to structure relationships and protein folding pathways
- The insertion of peptides and proteins into membranes
Intended Learning Outcomes
- An in-depth knowledge and understanding of the advanced protein biochemistry topics covered in the unit and an ability to keep abreast with recent developments in the field.
- The ability to gather information from the primary scientific literature and to critically evaluate the material and appraise competing theories.
- An understanding of the importance of the study of protein structure and dynamics and an understanding of the experimental tools used to study them.
- An understanding of reaction kinetics and the experimental tools used in the study of kinetics.
Teaching Information
Asynchronous lectures and synchronous discussion sessions.
Assessment Information
Assessment for learning (formative)
Students will undertake a mock assessment exercise.
Assessment of learning (summative)
The unit will be assessed as follows:
- 100% a timed assessment in January.
Reading and References
Reviews and primary articles from the current scientific literature.
