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Unit information: Transfusion and Transplantation Science (TTS-A1) in 2018/19

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Unit name Transfusion and Transplantation Science (TTS-A1)
Unit code PANMM0016
Credit points 20
Level of study M/7
Teaching block(s) Teaching Block 1 (weeks 1 - 12)
Unit director Dr. Mallinson
Open unit status Not open
Pre-requisites

None

Co-requisites

None

School/department School of Cellular and Molecular Medicine
Faculty Faculty of Life Sciences

Description

This Unit provides the basic science which underpins the applied and clinical aspects of Transfusion and Transplantation Sciences.

Aims:

To revise the biology and chemistry of proteins, DNA and PCR techniques

To introduce bacteria, prions, viruses relevant to transfusion to students

To teach the biology of red cells, white cells and platelets (their formation, structure antigen expression and normal turnover) and normal haemostasis.

To teach the techniques of blood cell grouping, and genoptyping.

To explain the use of flow cytometry as a tool in cell biology

To introduce the students to postgraduate study with several study skills sessions aimed to develop high level writing and appraisal of scientific literature.

Intended learning outcomes

Upon completion of the Unit students should have:

1. A broad and in depth understanding of normal physiology the human blood system.

2. A critical awareness and understanding of techniques relevant to transfusion and transplantation such as blood grouping, genotyping, flow cytometry and PCR.

And should be able to:

3. Show originality in the discussion and synthesis of information

4. Deal with complex issues systematically and creatively for example by answering an exam question requiring information from several lectures.

5. Critically evaluate current research in the discipline

6. Communicate clearly using appropriate writing styles

7. Demonstrate independent learning ability following lectures and tutorials

8. Demonstrate use of the library, internet and other educational tools

9. Demonstrate the use of standard computer “Office” tools.

The above are assessed as follows:

Short exam questions 1,2

Exam essay questions 1,2,3,4,7

Assignment 1,2, 3,4,5,6,7,8,9

Teaching details

Lectures and tutorials. NB Contact hours per week refer to 15 per week for 3 weeks

Assessment Details

One 2000 word assignment (30% of Unit marks)

One 2 ½ hour exam with a section of short answers (approx ½ hour, 20% of Unit marks) and two essays (approx 2hr, 50% of Unit marks).

The essay section of the exam paper has been deemed a must-pass component requiring a pass mark of at least 50%.

Reading and References

Postgraduate Haematology 6th edition (Eds Hoffbrand, Catovsky & Tuddenham). Wiley-Blackwell

Transfusion Microbiology, (Eds Barbara, Regan Contreras). Cambridge Press

Human Blood Groups 3rd edition Geoff Daniels. Wiley-Blackwell

Essential Haematology 6th edition Hoffbrand & Moss. Wiley-Blackwell

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