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Unit information: Advanced Immunology in 2019/20

Please note: Due to alternative arrangements for teaching and assessment in place from 18 March 2020 to mitigate against the restrictions in place due to COVID-19, information shown for 2019/20 may not always be accurate.

Please note: you are viewing unit and programme information for a past academic year. Please see the current academic year for up to date information.

Unit name Advanced Immunology
Unit code PANM33001
Credit points 20
Level of study H/6
Teaching block(s) Teaching Block 4 (weeks 1-24)
Unit director Professor. Wuelfing
Open unit status Not open



3 from the attached level 6/H lecture units and Research Skills unit.

School/department School of Cellular and Molecular Medicine
Faculty Faculty of Life Sciences


This module is focussed on immunology currently at the cutting edge of research. The unit includes: Innate immunity, Antigen processing, Immune trafficking, Peripheral CD4 T cell differentiation, Signalling and signal transduction in T and B cells, CD8 T cell responses, Positive and negative selection during thymocyte development, Central and peripheral tolerance. The topic will include a session on flow cytometry, a research paper workshop and a data handling workshop.


This unit provides in-depth coverage of the cellular and molecular events that drive immune responses. It illustrates the development and differentiation of immune cells, how the immune system processes and recognises antigens, how immune cells home to the tissues of our body where they are needed and highlights the consequences of their communications. It demonstrates that the immune system needs control and how this is achieved to avoid disease.

Intended learning outcomes

Knowledge and understanding of current topics in innate and adaptive immunity, and of the scientific literature pertaining to the field and an ability to evaluate this literature critically.

Teaching details

Lectures, Data Handling Session, Journal Review Session

Independent study: Students are expected to study the recommended literature.

Assessment Details

Summative 2 hour written exam, to include 2 essays, one essay to be chosen from each section containing three questions.

Reading and References

Janeway's Immunobiology, K Weaver and C Weaver, 9th edition (2017) Garland Science ISBN:9780815345510

Reviews and primary articles from the current scientific literature.