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Unit information: Receptor signalling and non-drug therapies in 2019/20

Please note: Due to alternative arrangements for teaching and assessment in place from 18 March 2020 to mitigate against the restrictions in place due to COVID-19, information shown for 2019/20 may not always be accurate.

Please note: you are viewing unit and programme information for a past academic year. Please see the current academic year for up to date information.

Unit name Receptor signalling and non-drug therapies
Unit code PHPH30003
Credit points 20
Level of study H/6
Teaching block(s) Teaching Block 4 (weeks 1-24)
Unit director Professor. Kelly
Open unit status Not open

PHPH20011 Principles of Pharmacology 2A



School/department School of Physiology, Pharmacology & Neuroscience
Faculty Faculty of Life Sciences


Students study advanced topics covering receptor signalling, so as to learn how different types of metabotropic receptors (including G-protein-coupled receptors and receptor tyrosine kinases) and intracellular receptors generate their effects, by the modification of levels of intracellular messengers and modification of trafficking of receptor proteins into and out of the cell membrane. The Unit also covers the roles of many of these receptors in the function and dysfunction of cardiovascular disease, and the use of drugs acting at these receptors in the treatment of cardiovascular disease. Novel therapies for disease that are not based around small molecules (such as gene manipulation) are also discussed.

Intended learning outcomes

  • An in-depth knowledge and understanding of the advanced topics covered in the unit and an ability to keep abreast with recent developments in the relevant field.
  • The ability to gather information from the primary scientific literature and to critically evaluate the material and appraise competing theories.
  • The ability to integrate information from multiple sources and disseminate it in written accounts.
  • An understanding of the importance of specialist metabotropic receptor pharmacology and of the development of novel therapies.

Teaching details


Assessment Details

The unit will be assessed through an in-course essay (1000 words) (10%) and one 3 hour examination in May/June (90%).

Reading and References

Reviews and primary articles from the current scientific literature (updated by individual lecturers on an annual basis).